EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.14.13.243 | 1-butyne | effective inhibitor of toluene-dependent growth, presence results in the irreversible loss of toluene- and o-cresol-dependent O2 uptake activities. Presence of oxygen, supplied as H2O2, is required for inhibition by 1-butyne | Burkholderia cepacia | |
1.14.13.243 | 1-hexyne | effective inhibitor of toluene-dependent growth, presence results in the irreversible loss of toluene- and o-cresol-dependent O2 uptake activities | Burkholderia cepacia | |
1.14.13.243 | 2-hexyne | effective inhibitor of toluene-dependent growth, presence results in the irreversible loss of toluene- and o-cresol-dependent O2 uptake activities | Burkholderia cepacia | |
1.14.13.243 | 3-hexyne | effective inhibitor of toluene-dependent growth, presence results in the irreversible loss of toluene- and o-cresol-dependent O2 uptake activities | Burkholderia cepacia | |
1.14.13.243 | Acetylene | 10-50% vol/vol gas phase required for inhibition of growth on toluene | Burkholderia cepacia | |
1.14.13.243 | additional information | alkynes are specific, mechanism-based inactivators of toluene 2-monooxygenase, with acetylene being relatively ineffective compared to longer alkynes | Burkholderia cepacia |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.14.13.243 | Burkholderia cepacia | Q9ANX4 and Q9ANX0 and Q9ANX3 and Q8VSV8 and Q9ANX1 and Q8VSV9 | Q9ANX4 i.e. subunit tomA1, Q9ANX0 i.e. subunit tomA5, Q9ANX3 i.e. subunit TomA2, Q8VSV8 i.e. subunit TomA3, Q9ANX1 i.e. subunit TomA4, Q8VSV9 i.e. subunit TomA0 | - |
1.14.13.243 | Burkholderia cepacia G4 | Q9ANX4 and Q9ANX0 and Q9ANX3 and Q8VSV8 and Q9ANX1 and Q8VSV9 | Q9ANX4 i.e. subunit tomA1, Q9ANX0 i.e. subunit tomA5, Q9ANX3 i.e. subunit TomA2, Q8VSV8 i.e. subunit TomA3, Q9ANX1 i.e. subunit TomA4, Q8VSV9 i.e. subunit TomA0 | - |